Research

Environmental Toxicology

Environmental Impacts on Human Health

Fibrosis, autoimmunity, COPD, asthma, cancers of the lung and pleura, heart disease, developmental defects, chronic inflammatory diseases, air pollution, neurotoxins, cancers caused by environmental agents, epidemiology of asthma, autoimmune disorders, neurodegenerative disease, immunotoxicology, autoimmunity, gene-environment interactions, dioxins, toxicity of natural products, immune modulation by natural products, chemistry of air pollution, anticancer drug discovery, mechanisms of toxicity, metals, developmental toxicology, arsenic toxicology, cardiovascular effects, GPCR, respiratory toxicology, asthma, lung inflammation, fibrosis, autoimmune disease following exposure to silicates, asbestos, organophosphate toxicology.

Christopher Migliaccio, Research Assistant Professor; Ph.D. (immunology), University of California-Davis, 2000. Investigating the cellular and molecular mechanisms underlying regulation of the immune response.

Anthony Ward, Research Assistant Professor; Ph.D. (environmental chemistry), The University of Montana, 2001. Chemistry of air pollution in western Montana, and how air pollution events, such as forest fire smoke and winter inversions, relate to adverse respiratory effects including asthma.

Curtis Noonan, Assistant Professor, Ph.D. (environmental health/epidemiology), Colorado State University, 2000. Study of environmental risk factors and biomarkers for neurodegenerative disease, autoimmune disease, and asthma.

Lilian Calderón-Garcidueñas, Associate Professor; M.D., Ph.D. (toxicology), North Carolina, 2001. Chronic health effects of air pollution in the respiratory, cardiovascular and central nervous systems.

Fernando Cardozo-Pelaez, Associate Professor; Ph.D. (medical sciences), South Florida, 1996. The effect of environmental neurotoxins on DNA damage, DNA repair capacity, and neuronal function in the CNS.

Darrell A. Jackson, Associate Professor; Ph.D. (pharmacology/toxicology), Washington State, 1990. G-protein-coupled receptor signaling in neurological disorders including Alzheimer's disease, Parkinson's disease, and stroke.

Mark A. Pershouse, Associate Professor; Ph.D. (biomedical sciences), Texas-Houston Health Sciences Center, 1993. Molecular genetics of human cancer; genomic expression analysis for detection of toxic injury; cancer detection and diagnostics; role of SV40 virus in human cancers; bioinformatics, and mechanisms of asbestos toxicity.

Elizabeth A. Putnam, Associate Professor; Ph.D. (biomedical sciences), Texas-Houston Health Sciences Center, 1989. Gene-environment interactions in the development of disease, focusing on cancer and fibrotic disease development after asbestos exposure using both mouse models and human studies.

Kevan Roberts, Associate Professor; Ph.D. (immunology), Manchester (U.K.), 1984. Respiratory immunology, asthma, and environmental impacts that exacerbate asthma.

David M. Shepherd, Associate Professor; Ph.D. (environmental and molecular toxicology), Oregon State, 1999. Immunomodulation by nutraceuticals and dietary supplements with a special emphasis on chronic inflammatory diseases such as arthritis and asthma; mechanisms of immunotoxicity following exposure to environmental chemicals such as the halogenated aromatic hydrocarbons (e.g., TCDD and PCBs).

Howard D. Beall, Professor; Ph.D. (medicinal chemistry), Florida, 1991. Anticancer drug discovery and mechanisms of toxicity, diet and cancer prevention, toxicology of metals.

Richard J. Bridges, Professor; Ph.D. (biochemistry), Cornell, 1984. Pharmacology and toxicology related to excitatory amino acid transporters, receptors and glutamate-mediated neuropathology.

J. Douglas Coffin, Professor; Ph.D. (anatomy and cell biology), SUNY Health Sciences Center at Syracuse, 1989. Genetic basis of mammalian growth and development and the function of growth factors in those processes.

Andrij Holian, Professor; Ph.D. (chemistry), Montana State, 1975. Mechanisms of the development and exacerbation of lung inflammation leading to asthma, lung fibrosis, and autoimmune diseases.

Diana I. Lurie, Professor; Ph.D. (neuroscience), Pennsylvania, 1989. Development and regeneration of the nervous system. The effect of toxins such as lead on CNS development and the neural and glial response to injury.

Charles M. Thompson, Professor; Ph.D. (organic chemistry), California, Riverside, 1982. Medicinal and bioorganic chemistry, neurochemistry; synthesis of novel small molecule probes of protein structure and function; protein mass spectrometry and proteomics; oragnophosphorus inhibitors; pharmacophore development.

Charles L. Eyer, Professor Emeritus; Ph.D. (pharmacology), Washington State, 1976. Oxidative damage, metal neurotoxicity, cellular responses to stress.