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Jerry R. Smith
Associate Professor
Phone: (406) 243-5788
Email: jerry.smith@umontana.edu
Dr. Smith completed a B.S. degree in Pharmacy from the University of Georgia in Athens, GA (1967) and a Ph.D. in Pharmacology (1977) from the University of Mississippi in Oxford. After graduate school he accepted a position at The University of Montana and has been here since 1977.
RESEARCH STATEMENT
Work in my lab focuses on:
- Myocardial Preconditioning and Ischemia-Reperfusion Injury
- Diabetic Modification of Cardiovascular Function
- Drug Metabolism & Cytochrome P-450 Isozymes
- Interactions of Soluble Fibers and Cardioactive Drugs
- Perfluorohydrocarbons and Their Impact on Oxygen Deprivation
- Energetics of CNS Cells Exposed to Potential Neurotoxins
KEY PUBLICATIONS
Smith J.R., Botchek S., Manson R., and Jaksha J. In Vitro interactions of selected soluble fibers with the cardiovascular drugs, nicotinic acid (Niacin) and pentoxifylline. Proc. Western Pharmacology Society, 35:107-111, 1992.
Zhao L., Smith J.R., and Eyer C.L. Effects of a 100% perfluorooctylbromide emulsion on ischemia/reperfusion injury following cardioplegia. Biomat., Art. Cells, & Immob. Biotech. 23(4):513-517, 1995.
Tarr B.D., Fraser B.H., and Smith J.R. Aminoguanidine prevents the negative inotropy associated with rabbits on high-fat, high-cholesterol diets. Pharmaceutical Sciences 2:1-4,1996.
Elliott G.T., Comerford M.L., Smith J.R., and Zhao L. Myocardial ischemia/reperfusion protection using MPL-A is abrogated by the ATP-sensitive potassium channel blocker, glibenclamide. Cardiovascular Research 32:1071-1080, 1996.
Zhao L., Weber P.A., Smith J.R., Comerford M.L., and Elliot G.T. Role of inducible nitric oxide synthase in pharmacologic "preconditioning" with monophosphoryl lipid A. J. Molec. Cell. Cardiology 29:1567-1576, 1997.
Zhao L., Smith J.R., and Eyer C.L. Effects of a 100% perfluorooctylbromide emulsion on ischemia/reperfusion injury following cardioplegia. Biomat., Art. Cells, & Immob. Biotech. 23(4):513-517, 1995.
Tarr B.D., Fraser B.H., and Smith J.R. Aminoguanidine prevents the negative inotropy associated with rabbits on high-fat, high-cholesterol diets. Pharmaceutical Sciences 2:1-4,1996.
Elliott G.T., Comerford M.L., Smith J.R., and Zhao L. Myocardial ischemia/reperfusion protection using MPL-A is abrogated by the ATP-sensitive potassium channel blocker, glibenclamide. Cardiovascular Research 32:1071-1080, 1996.
Zhao L., Weber P.A., Smith J.R., Comerford M.L., and Elliot G.T. Role of inducible nitric oxide synthase in pharmacologic "preconditioning" with monophosphoryl lipid A. J. Molec. Cell. Cardiology 29:1567-1576, 1997.