Journal Club Presentations

BMED 593: Current Research Literature (Journal Club)

Journal Club Manuscripts for Fall 2007 and Spring 2008

Click here to access archived manuscripts from past meetings

 

Date Manuscript (click on title to view article)
5/8/08

Journal of Medicinal Chemistry - A Tetrazolyl-Substituted Subtype-Selective AMPA Receptor Agonist - Vogensen et al

(for Rajale presentation, May 8, 12:10 pm, SB 275)

4/24/08

Archives of Neurology - Loss of Apolipoprotein E Receptor LR11 in Alzheimer Disease - Scherzer et al

The Journal of Neuroscience - The Lipoprotein Receptor LR11 Regulates Amyloid beta Production and Amyloid Precursor Protein Traffic in Endosomal Compartments - Offe et al

Annals of Neurology - Neuronal LR11/SorLA Expression Is Reduced in Mild Cognitive Impairment - Sager et al

(for Levey seminar, Apr 25, 12:10 pm, SB 169)

4/17/08

Bioorganic & Medicinal Chemistry Letters - 2-Cyano-4-fluoro-1-thiovalylpyrrolidine analogues as potent inhibitors of DPP-IV - Haffner et al

(for McConn seminar, Apr 18, 12:10 pm, SB 169)

4/10/08

Annual Review of Medicine - Current Pharmacotherapy for Alzheimer's Disease - Lleo et al

Biochemical Pharmacology - Reductions in b-amyloid concentrations in vivo by the g-secretase inhibitors BMS-289948 and BMS-299897 - Anderson et al
(for Apr 10, 12:10 pm, SB 275)

4/3/08 Toxicology and Applied Pharmacology - Ligand-dependent interactions of the Ah receptor with coactivators in a mammalian two-hybrid assay - Zhang et al
(for Simones presentation, Apr 3, 12:10 pm, SB 275)
3/20/08 The Journal of Medicinal Chemistry - Imidazo[2,1-b]thiazole System: A Scaffold Endowing Dihydropyridines with Selective Cardiodepressant Activity - Budriesi et al
(for Sharma presentation, Mar 20, 12:10 pm, SB 275)
3/13/08 The Journal of Neuroscience - Extracellular Glutamate Concentration in Hippocampal Slice - Herman and Jahr
(for Hoffman presentation, Mar 13, 12:10 pm, SB 275)
3/6/08

Infection and Immunity - T Cells Are Essential for Bacterial Clearance, and Gamma Interferon, Tumor Necrosis Factor Alpha, and B Cells Are Crucial for Disease Development in Coxiella burnetii Infection in Mice - Andoh et al
(for Hayes presentation, Mar 6, 12:10 pm, SB 275)

2/28/08 Genomics - Modulatory effects of Echinacea purpurea extracts on human dendritic cells: A cell- and gene-based study - Wang et al
(for Benson presentation, Feb 28, 12:10 pm, SB 275)
2/21/08 American Journal of Respiratory Cell and Molecular Biology - Asymmetric Dimethylarginine Induces Oxidative and Nitrosative Stress in Murine Lung Epithelial Cells - Wells, Holian
(for Wells seminar, Feb 22, 12:10 pm, SB 169)
2/14/08

Journal of Immunology - Regulation of Eotaxin Gene Expression by TNF-alpha and IL-4 Through mRNA Stabilization: Involvement of the RNA-Binding Protein HuR1 - Atasoy et al
(for Atasoy seminar, Feb 15, 12:10 pm, SB 169)

PNAS - RNA-binding protein HuR enhances p53 translation in response to ultraviolet light irradiation - Mazan-Mamczarz et al
(for Atasoy seminar, Feb 15, 12:10 pm, SB 169)

2/7/08

The Journal of Pharmacology and Experimental Therapeutics - Multidrug Resistance Gene G1199A Polymorphism Alters Efflux Transport Activity of P-Glycoprotein - Woodahl et al
(for Feb 7, 12:10 pm, SB 275)

The Pharmacogenomics Journal - Pharmacogenomic associations in ABCB1 and
CYP3A5 with acute kidney injury and chronic kidney disease after myeloablative hematopoietic cell transplantation - Woodahl et al

(for Feb 7, 12:10 pm, SB 275)

12/6/07

Journal of Sleep Research - The nature of spontaneous sleep across adulthood - Campbell et al
(for Dec 6, 12:10 pm, SB 275)

11/29/07

Cell - Defective DNA Repair and Neurodegenerative Disease - Rass et al
(for Lyda seminar, Nov 30, 12:10 pm, SB 169)

Nature - DNA repair is limiting for haematopoietic stem cells during ageing - Nijnik et al
(for Lyda seminar, Nov 30, 12:10 pm, SB 169)

Nature - Resveratrol improves health and survival of mice on a high-calorie diet - Baur et al
(for Lyda seminar, Nov 30, 12:10 pm, SB 169)

11/15/07 Free Radical Biology & Medicine - Ethanol preconditioning protects against ischemia/reperfusion-induced brain damage: Role of NADPH oxidase-derived ROS - Wang et al
(for Beske presentation, Nov 15, 12:10 pm, SB 275)
11/8/07

Nature Neuroscience - Restructuring the Neuronal Stress Response with Anti-Glucocorticoid Gene Delivery -Kaufer et al
(for Nov 8, 12:10 pm, SB 275)

The Journal of Neuroscience - Enhancing Cognition after Stress with Gene Therapy - Nicholas et al
(for Nov 8, 12:10 pm, SB 275)

11/1/07 Toxicology and Applied Pharmacology - CD28 in thymocyte development and peripheral T cell activation in mice exposed to suspended particulate matter - Drela et al
(for Nov 1, 12:10 pm, SB 275)
10/25/07

Journal of Biological Chemistry - Vesicular Glutamate Transporter Contains Two Independent Transport Machinerie - Juge et al
(for Chao seminar, Oct. 26, 12:10pm, SB 169)

10/18/07

Journal of Virology - Inhibition of Interferon-Stimulated JAK-STAT Signaling by a
Tick-Borne Flavivirus and Identification of NS5 as an Interferon Antagonist - Best et al

(for Greil seminar, Oct 19, 12:10 pm, SB 117)

Journal of Virology - Identification of Residues Critical for the Interferon Antagonist
Function of Langat Virus NS5 Reveals a Role for the RNA-Dependent RNA Polymerase Domain - Park et al

(for Greil seminar, Oct 19, 12:10 pm, SB 117)

10/11/07 Toxicology - Long-term effects of ochratoxin A on fibrosis and cell death in human proximal tubule or fibroblast cells in primary culture - Schwerdt et al
(for Oct 11, 12:10 pm, SB 275)
10/4/07 Protein Expression & Purification - Biochemical and mass spectrometric characterization of the human CB2 cannabinoid receptor expressed in Pichia pastoris—Importance of correct processing of the N-terminus - Zhang et al
(for Guo presentation, Oct 4, 12:10 pm, SB 275)
9/27/07

Journal of Biological Chemistry - Acute Formation of Protease-resistant Prion Protein Does Not Always Lead to Persistent Scrapie Infection in Vitro - Vorberg et al
(for Greil seminar, Sept 28, 12:10 pm, SB 169)

Journal of Neuroscience - Uptake and Neuritic Transport of Scrapie Prion Protein
Coincident with Infection of Neuronal Cells - Magalha˜es et al

(for Greil seminar, Sept 28, 12:10 pm, SB 169)

9/20/07

Environmental Health Perspectives - Particulate Matter Exposure Impairs Systemic Microvascular Endothelium-Dependent Dilation - Nurkiewicz et al
(for Castronova seminar, Sept 21, 12:10 pm, SB 169)

Environmental Health Perspectives - Systemic Microvascular Dysfunction and Inflammation after Pulmonary Particulate Matter Exposure - Nurkiewicz et al
(for Castronova seminar, Sept 21, 12:10 pm, SB 169)

9/13/07

Toxicology Letters - 2,3,7,8-Tetrachlorodibenzo-p-dioxin modulates functional differentiation of mouse bone marrow-derived dendritic cells downregulation of RelB by 2,3,7,8-tetrachlorodibenzo-p-dioxin - Lee et al
(for Shepherd seminar, Sept 14, 12:10 pm, SB 169)

Toxicology and Applied Pharmacology - 2,3,7,8-Tetrachlorodibenzo-p-dioxin Affects the Number and Function of Murine Splenic Dendritic Cells and Their Expression of Accessory Molecules - Vorderstrasse et al
(for Shepherd seminar, Sept 14, 12:10 pm, SB 169)

9/6/07

NeuroToxicology - A rationale for lowering the blood lead action level from 10 to 2 mg/dL - Gilbert et al
(for Prins seminar, Sept 7, 12:10 pm, SB 169)

European Journal of Neuroscience - Exercise affects energy metabolism and neural plasticity-related proteins in the hippocampus as revealed by proteomic analysis - Ding et al
(for Prins seminar, Sept 7, 12:10 pm, SB 169)